林冬菊，女，博士，講師，碩士生導師。2017年畢業于沈陽藥科大學藥物分析專業，同年，進入Betvictor中文版工作。研究方向為藥物代謝、藥代動力學、藥物毒理研究。近年來，在Drug Metab. Dispos.，Chem. Res. Toxicol.，Toxicol. Lett.等國際學術期刊發表SCI論文多篇。

聯系方式：E-mail:lindo.ngju@163.com

主講課程及研究方向

1. 主講課程：藥劑學

2. 研究方向：藥物代謝、藥代動力學、藥物毒理研究

承擔科研項目

河北省自然科學基金，H2019201360，基于CYP酶研究甘草次酸對黃獨素B肝毒性的保護作用，2019/01-2021/12，在研，主持。

代表性論文

Lin DJ^*, Ma Q, Zhang YW, Peng ZY. Phenolic compounds with antioxidant activity from strawberry leaves: a study on microwave-assisted extraction optimization. Prep. Biochem. Biotechnol. 2020, 50: 874-882.

Lin DJ, Li WW, Tian XT, Peng Y, Zheng J^*. In Vitro DNA Adduction Resulting from Metabolic Activation of Diosbulbin B and 8-Epidiosbulbin E Acetate. Chem. Res.Toxicol. 2019, 32: 38-48.

Lin DJ, Li WW, Peng Y, Jiang CF, Xu YJ, Gao HY, Zheng J^*. Role of metabolic activation in 8-epidiosbulbin E acetate-induced liver injury: mechanism of action of the hepatotoxic furanoid. Chem. Res. Toxicol. 2016, 29: 359–366.

Lin DJ, Wang K, Guo XC, Peng Y, Zheng J^*. Lysine- and Cysteine-based Protein Adductions Derived from Toxic Metabolites of 8-Epidiosbulbin E Acetate. Toxicol.Lett. 2016, 264: 20-28.

Li WW，Lin DJ, Gao HY, Xu Y, Meng D, Smith CV, Peng Y, Zheng J^*. Metabolic Activation of Furan Moiety Makes Diosbulbin B Hepatotoxic. Arch. Toxicol. 2016, 90: 863-872.

Lin DJ, Guo XC, Gao HY, Cheng L, Cheng MS, Song SJ, Peng Y, Zheng J^*. In vitro and in vivo studies of the metabolic activation of 8-epidiosbulbin E acetate. Chem. Res. Toxicol. 2015, 28: 1737–1746.

Lin DJ, Li CY, Peng Y, Gao HY, Zheng J^*. Cytochrome P450-mediated metabolic activation of diosbulbin B. Drug Metab. Dispos. 2014, 42: 1727−1736.