宋雪晴,女,博士,碩士生導師。2020年于天津醫科大學藥學院獲藥理學專業博士學位。主要從事抗腫瘤藥物的設計合成和體内外活性機制研究工作,主持Betvictor中文版高層次人才科研啟動項目1項,河北省自然科學基金青年項目1項;參與國家級、省級科研項目6項。在相關領域國際學術期刊發表SCI論文16篇。E-mail: sxqing@hbu.edu.cn。
代表性論文
[1] Zhong-Ying Ma1,Xue-Qing Song1, Juan-Juan Hu1, Dong-Bo Wang, Xiao-Jing Ding, Rui-Ping Liu, Miao-Liang Dai, Fan-Yin Meng, Jing-Yuan Xu*. Ketoplatin in triple-negative breast cancer cells MDA-MB-231: High efficacy and low toxicity, and positive impact on inflammatory microenvironment. Biochemical Pharmacology, 2021, 188, 114523.
[2]Xue-Qing Song1, Rui-Ping Liu1, Shu-Qing Wang1, Zhe Li, Zhong-Ying Ma, Ran Zhang, Cheng-Zhi Xie, Xin Qiao, and Jing-Yuan Xu*. Anticancer Melatplatin prodrugs: high effect and low toxicity, MT1-ER-target and immune response in vivo.Journal of Medicinal Chemistry, 2020, 63, 6096−6106.
[3] Ming Liu1,Xue-Qing Song1, Yuan-Di Wu, Jing Qian*, and Jing-Yuan Xu*. Cu(II)-TACN complexes selectively induced antitumor activities in HepG-2 cells by DNA damage and mitochondrial-ROS-mediated apoptosis.Dalton Transactions, 2020, 49, 114–123.
[4]Xue-Qing Song1, Zhong-Ying Ma1, Yi-Gang Wu1, Miao-Liang Dai, Dong-Bo Wang, Jing-Yuan Xu* and Yangzhong Liu*. New NSAID-Pt(IV) prodrugs to suppress metastasis and invasion of tumor cells and enhance anti-tumor effectin vitro andin vivo[J].European Journal of Medicinal Chemistry, 2019, 167, 377−387.
[5]Xue-Qing Song1, Ya-Hong Liu1, Jia Shao1, Zhen-Lei Zhang, Cheng-Zhi Xie, Xin Qiao, Wei-Guo Bao*, and Jing-Yuan Xu*. Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone[J].European Journal of Medicinal Chemistry, 2018, 157, 188−197.