霍小位,女,博士,碩士生導師,畢業于北京協和醫學院。主要從事天然産物及小分子化合物的抗腫瘤活性及分子機制研究。
主持國家自然科學基金項目1項、河北省自然科學基金項目2項,河北省教育廳項目1項。發表SCI收錄論文20餘篇。主講課程《藥理學》、《人體解剖生理學》等。
聯系方式:huoxiaoweiforever@163.com
研究方向
1. 天然産物及小分子化合物的抗腫瘤活性篩選、抗腫瘤分子靶标及作用機理研究
2. 抗炎及抗氧化藥物活性篩選及分子機制研究
代表性論著
[1] MY Chen, Y Hou, N Chen, EL Yang, ZC Sun, HF Wu, XD Xu, JS Yang, GX Ma*, XW Huo*. Co-assemblies based on natural Hemslecin A and β-sitosterol as a new sight for synergistic anti-gastric cancer efficacy in TCM. Colloid and Interface Science Communications, 2022, 49.
[2] DL Chen#, ZC Sun#, YY Liu, ZY Li, HQ Liang, L Chen, XD Xu, JS Yang, GX Ma*, XW Huo*. Eleucanainones A and B: Two dimeric structures from the bulbs of Eleutherine americana with anti-MRSA activity. Organic Letters, 2020, 22(9).
[3] XW Huo#, CQ Liu#, L Gao, XD Xu, NL Zhu*, L Cao*. Hepatoprotective effect of aqueous extract from the seeds of Orychophragmus violaceus against liver injury in mice and HepG2 cells. International Journal of Molecular Sciences, 2017, 18(6): 1197.
[4] LL Zhang#, XW Huo#, YH Liao, FF Yang, L Gao, L Cao*. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways. Scientific Reports, 2017, 7(1).
[5] XW Huo, YM Jia, DY Liu, L Gao, LJ Zhang, LY Li, Y Qi*, L Cao*. Photodynamic diagnosis of gastric cancer using HPPH-CD. Rsc Advances, 2016, 6(45): 39216-39224.