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趙丹丹

更新時間:2024-09-24 10:37:14點擊次數:

趙丹丹,女,醫學博士,副教授,2018年碩博連讀畢業于哈爾濱醫科大學藥理學專業,2021年蘇州大學心血管病研究所博士後出站後留任副研究員,碩士生導師。2023年進入Betvictor中文版工作。研究方向為多潛能幹細胞的心肌細胞分化、心髒類器官構建以及非編碼RNA與心血管疾病分子機制。近年來,主持國家自然科學基金青年項目1項,中國博士後面上項目1項,以共同第一作者身份在相關領域發表SCI研究論文6篇。

聯系方式:E-mail: dandan0103@126.com

研究方向

1)非編碼RNA參與調控心髒疾病。

2)誘導多潛能幹細胞與心髒類器官。

科研項目

1)國家自然科學基金青年項目,82000263CircRNA ALPK2調控多潛能幹細胞向心肌細胞分化的作用及機制,2021.01-2023.1224萬元,在研,主持。

2)中國博士後科學基金面上項目,2018M642316,長鍊非編碼RNA-UCA1調控分選連接蛋白17抑制心肌梗死,2019.01-2021.065萬元,結題,主持。

代表性論文

(1) Zhao, Dandan; Li, Xuelian; Liang, Haihai; Zheng, Nan; Pan, Zhenwei; Zhou, Yuhong; Liu, Xiao; Qian, Ming; Xu, Bozhi; Zhang, Ying; Feng, Ying; Qili, Muge; Wu, Qiuxia; Yang, Baofeng; Shan, Hongli ; SNX17 produces anti-arrhythmic effects by preserving functional SERCA2a protein in myocardial infarction, International Journal of Cardiology, 2018, 272: 298-305.

(2) Zhao Dandan; Li Cui; Yan He; Li Tianyu; Qian Ming; Zheng Nan; Jiang Hua; Liu Li; XuBozhi; Wu Qiuxia; Li Xuelian; Liang Haihai; Shan Hongli ; Cardiomyocyte Derived miR-328 Promotes Cardiac Fibrosis by Paracrinely Regulating Adjacent Fibroblasts, Cellular Physiology and Biochemistry, 2018, 46(4): 1555-1565.

(3) Miao, Shumei; Zhao, Dandan; Wang, Xiaoxiao; Ni, Xuan; Fang, Xing; Yu, Miao; Ye, Lingqun; Yang, Jingsi; Wu, Hongchun; Han, Xinglong; Qu, Lina; Li, Lei; Lan, Feng; Shen, Zhenya; Lei, Wei; Zhao, Zhen-Ao; Hu, Shijun ; Retinoic acid promotes metabolic maturation of human Embryonic Stem Cell-derived Cardiomyocytes, Theranostics, 2020, 10(21): 9686-9701.

(4) Yang, Jingsi; Ding, Nan; Zhao, Dandan; Yu, Yunsheng; Shao, Chunlai; Ni, Xuan; Zhao, ZhenAo; Li, Zhen; Chen, Jianquan; Ying, Zheng; Yu, Miao; Lei, Wei; Hu, Shijun ; Intermittent Starvation Promotes Maturation of Human Embryonic Stem Cell-Derived Cardiomyocytes, Frontiers in Cell and Developmental Biology, 2021, 9: 687769.

(5) Zhao, Dandan; Lei, Wei; Hu, Shijun ; Cardiac organoid - a promising perspective of preclinical model, Stem cell research & therapy, 2021, 12(1): 272.

 

(編輯:姜浩)
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