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劉鳳潔

更新時間:2024-06-20 17:33:18點擊次數:

劉鳳潔,博士,博士後,助理研究員。2020年畢業于中國藥科大學,獲生藥學博士學位,2023年于中國藥科大學中藥學博士後流動站出站,現就職于Betvictor中文版。

研究方向為中藥藥效物質基礎。近年來,主持國家自然科學基金青年項目1項,河北省高等學校科學技術研究項目1項,以第一作者或通訊作者身份發表SCI論文7篇。

聯系方式:liufj_cpu@126.com

研究方向:

(1)    中藥活性成分發現與作用機制研究;

(2)    基于組學技術和網絡醫學框架系統揭示中藥治病機理。

科研項目:

(1)    成分譜-靶點譜-互作網絡探究蒲公英治療三陰乳腺癌的藥效物質與作用機制,國家自然科學基金青年科學基金,821043632022/1~2024/1230萬,在研,主持

(2)    蒲公英效應物質及其協同抗腫瘤作用機制研究,河北省高等學校科學技術研究青年拔尖人才項目,BJK20241532024/01 ~2026/1210萬,在研,主持。

代表性論文:

1.      Yu T, Chen JM, Liu W, Zhao JQ, Li P, Liu FJ*, Jiang,Y* Li HJ*, In-depth characterization of cycloartane triterpenoids and discovery of species-specific markers from three Cimicifuga species guided by a strategy that integrates in-source fragment elimination, diagnostic ion recognition, and feature-based molecular networking, Journal of Chromatography A, 2024, 1728: 465015.

2.       Liu FJ1, Chen XY1, Yang J, Zhao Z, Wang QL, Li P, Jiang Y*, Li HJ*. Revealing active components and action mechanism of Fritillariae Bulbus against non-small cell lung cancer through spectrum-effect relationship and proteomics. Phytomedicine, 2023, 110: 154635.

3.      Liu FJ1*, Yang J1, Chen XY, Yu T, Ni H, Feng L, Li P, Li HJ*. Chemometrics integrated with in silico pharmacology to reveal antioxidative and anti-inflammatory markers of dandelion for its quality control. Chinese Medicine, 2022, 17: 125.

4.      Liu FJ, Jiang Y, Li P, Liu YD, Yao ZP*, Xin GZ*, Li HJ*. Untargeted metabolomics coupled with chemometric analysis reveals species-specific steroidal alkaloids for the authentication of medicinal Fritillariae Bulbus and relevant products, Journal of Chromatography A, 2020, 1612: 460630.

5.      Liu FJ, Jiang Y, Li P*, Liu YD, Xin GZ, Yao ZP*, Li HJ*. Diagnostic fragmentation-assisted mass spectral networking coupled with in silico dereplication for deep annotation of steroidal alkaloids in medicinal Fritillariae Bulbus, Journal of Mass Spectrometry, 2020, 55: e4528.

6.      Liu FJ, Liang D, Miao LY, Li P, Li HJ*. Liver-specific metabolomics characterizes the hepatoprotective effect of saponin-enriched Celosiae Semen extract on mice with nonalcoholic fatty liver disease, Journal of Functional Foods, 2018, 42: 185-194.

7.      Liu FJ, Zhu ZH, Jiang Y*, Li HJ*. A pair of cyclopeptide epimers from the seeds of Celosia argentea. Chinese Journal of Natural Medicine, 2018, 16: 63-69.

(編輯:姜浩)
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