郝雪芳，女，博士，講師。2012年7月畢業于Betvictor中文版高分子材料與工程專業，2012年9月至2018年6月就讀于天津大學應用化學專業醫用高分子材料方向，獲工學碩士和博士學位。主持省級及以下項目兩項，在Chem. Eng. J., Acta Biomater., ACS Appl. Mater. Interfaces, Biomater. Sci.等學術期刊發表SCI論文20餘篇。
E-mail：hxf15175374404@126.com
研究方向
聚合物材料的合成
多功能基因/藥物遞送系統的設計、制備及應用研究
科研項目
1.内蒙古自治區高等學校科學研究重點項目，靶向仿生熒光納米體系的構建及其在腫瘤成像和治療中的研究（NJZZ20109），2020.01-2022.12，6萬，結題，主持。
2.内蒙古自治區自然科學基金項目，pH響應性仿生藥物遞送系統抑制血管再狹窄的研究（2019BS08005），2019.01-2021.12，10萬，結題，主持。
近年發表的代表性論文
1. Xuefang Hao*; Weiwei Gai; Yanping Zhang; Weitong Zhou; Yakai Feng*; Biomimetic and inflammation-targeted nanoparticles for rheumatoid arthritis therapy via M1-macrophages apoptosis and polarization, Materials & Design, 2024, 239: 112806.
2. Xuefang Hao*; Weiwei Gai; Yanping Zhang; Dandan Zhao; Weitong Zhou; Yakai Feng*; Peptide functionalized biomimetic gene complexes enhance specificity for vascular endothelial regeneration, Colloids and Surfaces B: Biointerfaces, 2024, 114020.
3. Xuefang Hao*; Qian Li; Recent Advances in Cell‐Based Nanotherapy for Cardiovascular Diseases, Macromolecular Bioscience, 2023, 23(7): 2200537.
4. Xuefang Hao*; Weiwei Gai; Feng Ji; Lina Wang; Jiadi Zhao; Fan Yang; Haixia Jiang; Yakai Feng*; Biomimetic and responsive nanoparticles loading JQ1 for dual-targeting treatment of vascular restenosis via multiple actions, Chemical Engineering Journal, 2022, 431(4):133452.
5. Xuefang Hao*; Weiwei Gai; Feng Ji; Jiadi Zhao; Dandan Sun; Fan Yang; Haixia Jiang; Yakai Feng*; Bovine serum albumin-based biomimetic gene complexes with specificity facilitate rapid re-endothelialization for anti-restenosis, Acta Biomaterialia, 2022, 142: 221-241.
6. Xuefang Hao*; Weiwei Gai; Lina Wang; Jiadi Zhao; Dandan Sun; Fan Yang; Haixia Jiang; Yakai Feng*; 5-Boronopicolinic acid-functionalized polymeric nanoparticles for targeting drug deliveryand enhanced tumor therapy, Materials Science & Engineering C, 2021, 119: 111553.
7. Weiwei Gai; Xuefang Hao*; Jiadi Zhao; Lina Wang; Jinghai Liu; Haixia Jiang; Hua Jin; Guoli Liu; Yakai Feng*; Delivery of benzoylaconitine using biodegradable nanoparticles to suppress inflammation via regulating NF-κB signaling, Colloids and Surfaces B: Biointerfaces, 2020, 191: 110980.
8. Xuefang Hao; Qian Li; Huaning Wang; Khan Muhammad; Jintang Guo; Xiangkui Ren; Changcan Shi; Shihai Xia; Wencheng Zhang; Yakai Feng; CAGW modified polymeric micelles with different hydrophobic cores for efficient gene delivery and capillary-like tube formation, ACS Biomater. Sci. Eng., 2018, 4: 2870-2878.
發明專利
1. 郝雪芳，蓋微微，基于蛋白和血小闆膜修飾的基因遞送系統制備方法和應用，2022-12-13，中國，ZL202011403571.1
2. 郝雪芳，蓋微微，一種多功能高效藥物遞送系統及其制備方法和應用，2023-08-11，中國，ZL202011606510.5
